CYP2B6*24 (c.1427G>A, p.G476D) – Uncertain function: CYP2B6*24 is assigned uncertain function. In vitro studies using cDNA expression systems found that CYP2B6*24 had no enzyme activity towards several substrates compared to the *1 reference (20517174, 21746968, 30201214). However, there was no in vivo data available or data in human liver microsomes. Therefore, consensus among experts was uncertain function based on inadequate evidence.