This result signifies that the patient has one copy of a decreased function allele and one copy of a no function allele of the DPYD gene. Based on the genotype result this patient is predicted to be a DPYD Poor Metabolizer with a DPYD activity score of 0.5. This patient may be at risk for adverse drug reactions to medications that are metabolized by DPD (i.e. 5-fluorouracil, capecitabine, and tegafur) and a dose adjustment or alternative therapeutic agents may be indicated. Please consult a clinical pharmacist for more information about how DPD metabolic status influences drug selection and dosing.