NUDT15*10 is assigned no function based on limited evidence. While there is no literature describing function for NUDT15*10, c.2T>C is predicted to disrupt protein translation due to the loss of the canonical start codon, and there is no alternative start codon available. Three out of seven variant effect predictors tested by CPIC staff predict that the NUDT15*10 SNV (c.2T>C) impairs protein function.