{"6-mercaptopurine can be affected by a patient's TPMT and NUDT15 phenotype. This patient is predicted to be a NUDT15 normal metabolizer; there is no reason to selectively adjust the dose of this medication based on the NUDT15 result. Because a TPMT genotype does not appear to have been ordered for this patient, it is not known if TPMT results would influence the recommended dose or drug. If thiopurines are required and TPMT genotype status is unknown, consider evaluating TPMT erythrocyte activity to assess TPMT phenotype. Erythrocyte TPMT activity test results can be falsely low at diagnosis of leukemia and is unreliable in the case of recent red blood cell transfusions. Please consult a clinical pharmacist for more information."}